OVERVIEW

The department has been provided with air-conditioned lecture theatre of 200 capacity equipped with IT compatible LCD presentation facilities, conventional OHP and white board to facilitate blended teaching learning sessions. For small group teaching, there are one-demonstration rooms with 80 seating capacity. 

For practicing laboratory skills, the department of biochemistry has well equipped practical laboratory with advanced biochemical instruments as well clinical biochemistry lab in the hospital.

Course objectives and contents

(i) GOAL

The broad goal of the teaching of undergraduate students in biochemistry is to make them understand the scientific basis of the life processes at the molecular level and to orient them towards the application of the knowledge acquired in solving clinical problems.

(ii) OBJECTIVES

a. KNOWLEDGE

describe the molecular and functional organization of a cell and list its subcellular components;?delineate structure, function and inter-relationships of biomolecules and consequences of deviation from normal;

summarize the fundamental aspects of enzymology and clinical application wherein regulation of enzymatic activity is altered;?describe digestion and assimilation of nutrients and consequences of malnutrition; integrate the various aspects of metabolism and their regulatory pathways;

explain the biochemical basis of inherited disorders with their associated sequelae; describe mechanisms involved in maintenance of body fluid and pH homeostasis;?outline the molecular mechanisms of gene expression and regulation, the principles of genetic engineering and their application in medicine;?summarize the molecular concepts of body defence and their application in medicine; outline the biochemical basis of environmental health hazards, biochemical basis of cancer and carcinogenesis;?familiarize with the principles of various conventional and specialized laboratory investigations and instrumentation analysis and interpretation of a given data;

the ability to suggest experiments to support theoretical concepts and clinical diagnosis.

At the end of the course, the student should be able to :

b. SKILLS

At the end of the course, the student should be able to :

make use of conventional techniques/instruments to perform biochemical analysis relevant to clinical screening and diagnosis;

analyze and interpret investigative data;?demonstrate the skills of solving scientific and clinical problems and decision making;

c. INTEGRATION

The knowledge acquired in biochemistry should help the students to integrate molecular events with structure and function of the human body in health and disease.

Outline of the Course Content

The teaching hours for total physiology course will be 480 hrs. which Including Lectures, Practicals, Tutorials, Demonstrations & Seminars. Broad distribution of teaching hours is as given below:

Didactic Lectures                                                                   

Demonstrations                                                         

Dissection hours

Histology Practicals,                                                              

Tutorials,

Museum rounds for self study                                                                       

Group learning sessions                                 

Seminars & Symposium                                                10

Integrated T-L sessions                                                 20

Biochemistry Department conducts a wide spectrum clinical investigations and diagnosis of the dieses. The department is having a well maintained lecture hall, Demonstration Room, Student Practical Lab, and a Research Lab.

The students of MBBS First Professional will be able to understand various biochemical reactions of metabolic pathways in normal and pathological conditions.     

Syllabus (Biochemistry)

1. Cell membrane, 
2.  
3. Chemistry and metabolism of Fat and Carbohydrates and proteins, 
4.  
5. Enzymes Body Fluids
6.  
7. pH buffers. Acid base balance and regulation
8.  
9. Biological oxidation
10.  
11. Body defense mechanism And its application in medicine.
12.  
13. Environmental Biochemistry and Cancer Biochemistry, 
14.  
15. Organ Function Tests, Newer Techniques. 
16.  
17. Protein chemistry and Metabolism,
18.  
19. Nucleic and Transcription,
20.  
21. Replication,
22.  
23. Molecular Biology, Genetic Engineering Bio-Technology,
24.  
25. Integration of Metabolism
26.  
27. Purine, Pyrimidine Chemistry, And Metabolism
28.  
29. Vitamins, Minerals and Nutrition.