OVERVIEW

Biochemistry is the branch of science that explores the biochemical processes within and related to living organisms. It is a laboratory based science that brings together Chemistry and Biology. By using chemical knowledge and techniques, students can understand and solve biological problems. Biochemistry allows us to understand how chemical processes, such as respiration, produce life functions in all living organisms. The department of Biochemistry offers a high quality learning environment for students within a high powered research program. The department is developing the world’s next well qualified doctors, scientists and researchers at Rajshree Medical Research Institute. The focus of the department is to develop a fascination and passion that enables the students to strive for success in their future endeavours.

Pedagogy & Facilities

The pedagogy is highly interactive at the department of biochemistry. It leverages use of technology and consists of a judicious blend of lectures, real life cases, problems, quizzes, assignments, demonstrations, laboratory work, etc. The Biochemistry department of Rajshree Institute is festooned with well-equipped laboratories and provides round the clock lab services. The Clinical Laboratory of the department provides biochemical investigations. The department is pursuing research in almost all areas of modern biochemistry including proteomics, toxicology, molecular biology, microbiology, clinical biochemistry, etc. Besides it, all teaching and non-teaching staff members are motivated towards research activity and sincere effort is made to submit research proposals to funding agencies. They are also actively involved in patient care with constant effort to update the diagnostic panel. The faculty and staff members are actively involved in co-curricular activities like organization of conferences seminars, CMEs and guest lectures. A well-organized departmental library having a generous collection of books, magazines, periodicals, journals, etc. The atmosphere of the department encourages a healthy flow and exchange of ideas among faculty members and students.

Key Features:

  • Excellence in teaching
  • Focus on research activities
  • Individual attention to every student
  • Personal guidance
  • Career Counseling
  • Encourages exchange of ideas among faculty members and students

Course objectives and contents:

(i) GOAL

The broad goal of the teaching of undergraduate students in biochemistry is to make them understand the scientific basis of the life processes at the molecular level and to orient them towards the application of the knowledge acquired in solving clinical problems.

(ii) OBJECTIVES

a. KNOWLEDGE

describe the molecular and functional organization of a cell and list its subcellular components;?delineate structure, function and inter-relationships of biomolecules and consequences of deviation from normal;

summarize the fundamental aspects of enzymology and clinical application wherein regulation of enzymatic activity is altered;?describe digestion and assimilation of nutrients and consequences of malnutrition; integrate the various aspects of metabolism and their regulatory pathways;

explain the biochemical basis of inherited disorders with their associated sequelae; describe mechanisms involved in maintenance of body fluid and pH homeostasis;?outline the molecular mechanisms of gene expression and regulation, the principles of genetic engineering and their application in medicine;?summarize the molecular concepts of body defence and their application in medicine; outline the biochemical basis of environmental health hazards, biochemical basis of cancer and carcinogenesis;?familiarize with the principles of various conventional and specialized laboratory investigations and instrumentation analysis and interpretation of a given data;

the ability to suggest experiments to support theoretical concepts and clinical diagnosis.

At the end of the course, the student should be able to :

b. SKILLS

At the end of the course, the student should be able to :

make use of conventional techniques/instruments to perform biochemical analysis relevant to clinical screening and diagnosis;

analyze and interpret investigative data;?demonstrate the skills of solving scientific and clinical problems and decision making;

c. INTEGRATION

The knowledge acquired in biochemistry should help the students to integrate molecular events with structure and function of the human body in health and disease.

Outline of the Course Content:

The teaching hours for total physiology course will be 480 hrs. which Including Lectures, Practicals, Tutorials, Demonstrations & Seminars. Broad distribution of teaching hours is as given below:

Didactic Lectures

Demonstrations

Dissection hours

Histology Practicals,

Tutorials

Museum rounds for self study

Group learning sessions

Seminars & Symposium                                                10

Integrated T-L sessions                                                 20

Biochemistry Department conducts a wide spectrum clinical investigations and diagnosis of the dieses. The department is having a well maintained lecture hall, Demonstration Room, Student Practical Lab, and a Research Lab.

The students of MBBS First Professional will be able to understand various biochemical reactions of metabolic pathways in normal and pathological conditions.

Syllabus (Biochemistry):

  1. Cell membrane
  2. Chemistry and metabolism of Fat and Carbohydrates and proteins
  3. Enzymes Body Fluids
  4. pH buffers. Acid base balance and regulation
  5. Biological oxidation
  6. Body defense mechanism And its application in medicine
  7. Environmental Biochemistry and Cancer Biochemistry
  8. Organ Function Tests, Newer Techniques
  9. Protein chemistry and Metabolism
  10. Nucleic and Transcription
  11. Replication
  12. Molecular Biology, Genetic Engineering Bio-Technology
  13. Integration of Metabolism
  14. Purine, Pyrimidine Chemistry, And Metabolism
  15. Vitamins, Minerals and Nutrition

Key Specialist

DR. AJAYA KUMAR ANAND

ASSOCIATE PROFESSOR